according to Peter Rogers, professor in the department of experimental psychology, at the University of Bristol, England, caffine, in a neurological sense, acts upon the central nervous system, affecting the neurotransmitters in the neurons that produce adenosine. adenosine affects the blood pressure, alertness, anxiety response, and sleepiness of the body. after experimenting on a select group of people with specific, controlled amount of caffine content, it was found that those given a caffine placebo (who had been accustomed to much higher doses in their daily routine) suffered an acute withdrawl: participants began to experience increased anxiety, sudden headaches, and some developed a "caffine hangover". Please view the study.